
Malcolm’s older brothers — Christopher Masterson as Francis and Justin Berfield as Reese — join the Malcolm in the Middle reunion filming in Vancouver this Spring.
Just started watching Malcolm in the Middle episode 1. Got 151 to catch up on before we start filming again in a few days!!! Can't wait to get back together with my old family.
— Frankie Muniz (@frankiemuniz) March 24, 2025
Malcolm (Frankie Muniz) and his daughter (Keeley Karsten) are drawn into the family’s chaos when Hal (Bryan Cranston) and Lois (Jane Kaczmarek) demand his presence for their 40th wedding anniversary party.

Malcolm’s younger brothers have been recast with Caleb Ellsworth-Clark playing adult Dewey and Anthony Timpano playing adult Jamie. Vaughan Murrae will play the sixth sibling Kelly, who was just a positive pregnancy test in the series finale.
Keeley Karsten will play adult Malcolm’s daughter, Leah.
Kiana Madeira will play adult Malcolm’s opinionated girlfriend Tristan.

The popular millennium sitcom, about a gifted teen trying to survive life with his dimwitted, dysfunctional family, ran for seven seasons from 2000-2006 and 151 episodes on Fox.

Malcolm in the Middle Limited Series:
Episodes 4.
Vancouver filming dates: April 13 2025 – May 15 2025.
Showrunner: Linwood Boomer.
Director: Ken Kwapis.
Cast: Frankie Muniz, Bryan Cranston, Jane Kaczmarek, Christopher Masterson, Justin Berfield, Caleb Ellsworth-Clark, Anthony Timpano,Vaughan Murrae, Kiana Maderia.
Sound stages: Vancouver Film Studios.
Producers: New Regency, 20th Television, Fox TV Studios.