
One Man. Two Lives. And A Mind He Can’t Trust.
Fox’s new Toronto-filmed series Memory of a Killer, starring Patrick Dempsey as a hitman with a secret family who’s losing his memory, has a two-night premiere starting tonight after the NFC Championship Game.
Part 2 of the premiere will air on Monday in the show’s regular time slot.
In Memory of a Killer, Angelo Ledda (Patrick Dempsey) lives two totally separate lives — fearsome NYC hitman and sleepy upstate Cooperstown photocopier salesman and father. Both of them are threatened when he is diagnosed with Alzheimer’s.
Michael Imperioli is Angelo’s oldest friend and employer Dutch, an Italian chef whose Bronx restaurant is the front for his criminal enterprise. Dutch gives Angela the targets for his hits.

Vancouver’s own Richard Harmon is Joe, a young hitman working for Angelo and Dutch. Joe gets stuck with the grunt work – gathering recon and sorting getaway plans – but that puts him in prime position to witness Angelo’s Alzheimer’s decline.

Odeya Rush is Angelo’s daughter Maria, who’s there to care for him as his mind begins to falter.
Fox’s Memory oF a Killer series is inspired by the 2003 Belgian thriller De Zaak Alzheimer (La Memoire Du Tueur) and its 2022 American movie adaption Memory starring Liam Neeson.
Memory of a Killer – Season One.

Toronto filming dates: August 11 2025 – January 23 2026.
Showrunners: Ed Whitmore, Tracey Malone, David Schulner.
Cast: Patrick Dempsey, Michael Imperioli, Richard Harmon, Odeya Rush, Alexandra Castillo, Peter Gadiot, Daniel David Stewart.
Producers: Fox.